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Clinical Trial Summary

This study evaluates the safety and efficacy of PHA-022121 administered orally for prophylaxis against angioedema attacks in patients with hereditary angioedema (HAE). The study consists of 2 parts, with patients completing participation in Part 1 prior to initiation of treatment in Part 2. Part 1 of the study has 3 parallel arms and approximately 30 patients will be equally randomized to one of two dose regimens of PHA-022121 or matching placebo. Patients will continue to the single open-label arm in Part 2 of the study after completion of Part 1. The screening period is up to 8 weeks and the treatment periods are 12 weeks (Part 1) and 30 months (Part 2) in duration.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05047185
Study type Interventional
Source Pharvaris Netherlands B.V.
Contact
Status Active, not recruiting
Phase Phase 2
Start date April 19, 2022
Completion date December 2026

See also
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