Clinical Trials Logo

Clinical Trial Summary

By July 9, 2020, the global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection had resulted in over 11.8 million confirmed cases and over 545000 deaths. Patients with a history of cardiovascular disease are especially vulnerable and have a bad prognosis. According to the findings, cardiac injury manifested by cardiac biomarker elevation is detected in a significant number of COVID-19 patients and is linked to poor outcomes and mortality. However, it is unclear how effective cardiac biomarkers are in COVID-19 prognosis and how to use these indicators.

Clinical Trial Description

The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has led to >11.8 million confirmed cases with >545000 deaths worldwide by July 9, 2020 Patients with preexisting cardiovascular conditions are particularly at risk and have poor prognosis data suggest that cardiac injury, manifested by cardiac biomarker elevation, is detected in a sizable of COVID-19 patients and is associated with adverse outcomes and increased mortality. However, how useful cardiac biomarkers are in COVID-19 prognosis and how to utilize these markers have not been well defined The study will include all moderate to severe COVID 19 patients admitted to ICU. Both genders within the age group 18-60 years were included. The primary outcome is the relation between cardiac markers and mortality rate in critically ill COVID 19 patients The secondary outcome is the relationship between cardiac and inflammatory and coagulation markers ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05040750
Study type Observational
Source Ain Shams University
Contact Rania M Hussien, MD
Phone 026213948
Email [email protected]
Status Recruiting
Start date September 1, 2021
Completion date November 30, 2021

See also
  Status Clinical Trial Phase
Recruiting NCT04573049 - The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement Phase 4
Not yet recruiting NCT03899298 - Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions Phase 1
Terminated NCT03208023 - RESIPI for Reducing Perioperative Major Adverse Cardiac Events N/A
Recruiting NCT04596163 - Transversus Thoracis Muscle Plane Block for Sternotomy Pain in Cardiac Surgery N/A
Completed NCT03407573 - Restrictive vs Liberal Transfusion Strategy on Cardiac Injury in Patients Undergoing Surgery for Fractured Neck Of Femur N/A
Completed NCT03916861 - BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy N/A
Recruiting NCT04156594 - Preoperative Self-assessment for Cardio-pulmonary Risk Stratification
Enrolling by invitation NCT04002531 - A One Visit Follow Up of Adults With Fabry Disease Who Started Long-term Enzyme Replacement Therapy As Children N/A
Completed NCT01830023 - Vitality Trial - Sampling Examination Data N/A
Not yet recruiting NCT04696523 - Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage Phase 2
Recruiting NCT04749147 - Color Priming and Patient Decision-Making in the Emergency Department: Priming "Threat" in Patients With Low-Risk Chest Pain N/A
Recruiting NCT04499612 - Influence of Cardiac Implantable Electronic Devices on the Hemostatic System
Recruiting NCT03646760 - The Improving ATTENDance to Cardiac Rehabilitation Trial N/A
Not yet recruiting NCT03355170 - Cardiac Safety of Lansoprazole and Domperidon Combination Phase 4
Completed NCT00750958 - PREVENT - Prospective Rhythm Event Surveillance in the ER With NetGuard N/A
Completed NCT04492384 - Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients
Recruiting NCT03932604 - Atrial Sensing Capability for Better Detection of Atrial Fibrillation N/A
Completed NCT04824586 - Intraoperative Insulin Administration at Cardiac Surgery for Diabetic Patients Phase 4
Completed NCT02814084 - Prevena Incision Management N/A
Withdrawn NCT02850250 - Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery