Clinical Trials Logo

Clinical Trial Summary

Prospective, nonrandomized, single-center, comparative study to define if right ventricular (RV) contractile reserve assessed by exercise CMR helps to improve the differential diagnosis between pathological and physiological remodeling of the RV; ie. arrhythmogenic right ventricular cardiomyopathy (ARVC) and athlete's heart.


Clinical Trial Description

Comparison of the RV contractile reserve in 4 groups of patients: Arrhythmogenic right ventricular cardiomyopathy (ARVC) patients; endurance athletes with a dilated RV, endurance athletes with normal RV, untrained subject with normal RV. Patients will come to the hospital for 3 visits (3 half days): - Visit 1: clinical evaluation, rest ECG, rest echocardiography, cardio-pulmonary exercise test. - Visit 2: exercise echocardiography, holter ECG monitor (48 yours) - Visit 3: rest CMR and exercise CMR (ergocycle) ;


Study Design


Related Conditions & MeSH terms

  • Arrhythmogenic Right Ventricular Cardiomyopathy
  • Arrhythmogenic Right Ventricular Dysplasia
  • Cardiomyopathies

NCT number NCT05024708
Study type Interventional
Source Rennes University Hospital
Contact Frédéric SCHNELL, MD-PhD
Phone +33 2.99.28.41.33
Email Frederic.SCHNELL@chu-rennes.fr
Status Recruiting
Phase N/A
Start date January 16, 2023
Completion date January 16, 2024

See also
  Status Clinical Trial Phase
Completed NCT03177018 - DNA Analysis From Isolated Cardiomyocytes in the Molecular Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia N/A
Recruiting NCT05799833 - Low QRS Voltages in Young Healthy Individuals and Athletes
Recruiting NCT03061994 - Metabolomic Study of All-age Cardiomyopathy N/A
Completed NCT00292032 - Registry of Unexplained Cardiac Arrest
Completed NCT04124237 - Long Term Monitoring for Risk of Sudden Death
Enrolling by invitation NCT03527342 - Sahlgrenska Cardiomyopathy Project
Completed NCT03685149 - Pilot Randomized Trial With Flecainide in ARVC Patients Phase 2
Recruiting NCT03076580 - An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China
Completed NCT02302274 - Diagnostic Value and Safety of Flecainide Infusion Test in Brugada Syndrome
Recruiting NCT06311708 - Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Recruiting NCT03572569 - Risk Stratification in Children and Adolescents With Primary Cardiomyopathy
Completed NCT01804699 - National ARVC Data Registry and Bio Bank
Recruiting NCT03049254 - Mayo AVC Registry and Biobank
Recruiting NCT02989480 - PET-detected Myocardial Inflammation is a Characteristic of Cardiac Sarcoid But Not of ARVC
Completed NCT02291393 - The Role of High Density Surface ECG in the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) N/A
Recruiting NCT04265040 - DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies
Recruiting NCT06040242 - Arrhythmogenic Activity During Exercise in ARVC Patients N/A
Recruiting NCT02432092 - Pediatric Cardiomyopathy Mutation Analysis
Active, not recruiting NCT04895540 - South Asian Arrhythmogenic Cardiomyopathy Registry
Recruiting NCT06228924 - Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC Phase 1