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A Single-arm Phase II Study to Evaluate the Safety and Efficacy of Combination Systematic Chemotherapy and Multiple Rounds of Endoscopic Ultrasound-guided Radiofrequency Ablation in Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma (PDAC) Clinical Trial

Official title:
A Single-arm Phase II Study to Evaluate the Safety and Efficacy of Combination Systematic Chemotherapy and Multiple Rounds of Endoscopic Ultrasound-guided Radiofrequency Ablation in Pancreatic Cancer

Clinical Trial Summary

The objectives of this study are to determine the feasibility, tolerability, and treatment effect of Endoscopic Ultrasound (EUS) Radiofrequency ablation (RFA) plus standard-of-care Neoadjuvant chemotherapy (NAC) in the treatment of Pancreatic Ductal Adenocarcinoma (PDAC). Endoscopic Ultrasound (EUS) Radiofrequency ablation (RFA) and Neoadjuvant chemotherapy (NAC) will be performed before tumor resection surgery, with the goal of shrinking a tumor or stopping the spread of cancer so that surgery might be less invasive and more effective.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Pancreatic Ductal Adenocarcinoma (PDAC)
Clinical Trial Details
NCT number NCT04990609
Study type Interventional
Source The University of Texas Health Science Center, Houston
Contact Prithvi B Patil, MS
Phone 7135006456
Email prithvi.b.patil@uth.tmc.edu
Status Recruiting
Phase Phase 2
Start date August 13, 2021
Completion date January 30, 2028
View Details
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