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Clinical Trial Summary

The purpose of this study is to compare the efficacy, safety and imaging outcomes between Anterior Controllable Antedisplacement and Fusion (ACAF) and Laminoplasty in the treatment of severe ossification of cervical posterior longitudinal ligament.


Clinical Trial Description

This is a national, multicenter, prospective, randomized controlled trial to compare the safety and efficacy of ACAF and posterior laminoplasty in the treatment of severe ossification of cervical posterior longitudinal ligament. In this study, 164 adult patients aged 18-70 with severe copll were randomly assigned to the experimental group (using ACAF) and the control group (using lamp) according to the ratio of 1:1. The patients were followed up for 2 years. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04968028
Study type Interventional
Source Shanghai Changzheng Hospital
Contact Dan Han, Master
Phone +86 18317028536
Email changzhengspine@163.com
Status Recruiting
Phase N/A
Start date August 17, 2021
Completion date December 31, 2026

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