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A Phase II Study of Sintilimab Combined With Anlotinib in Treatment of ED-SCLC

Small Cell Lung Cancer Extensive Stage Clinical Trial

Official title:
Anti-PD-1 Antibody Sintilimab Combined With Anti-angeogensis Inhibitor Anlotinib in Treatment of Extensive-stage Disease Small Cell Lung Cancer After Failure of First Line Standard Therapy : a Single-arm Prospective Phase II Clinical Study

Clinical Trial Summary

This is a the researchers launched, single-center, prospective, open-label, single arm ,Phase II clinical study of Sintilimab combined with anlotinib in patients with extensive-stage disease small-cell lung cancer to evaluate the efficacy and safety. 23 patients are expected to be enrolled in this study.

Clinical Trial Description

Subjects will receive sintilimab 200mg, IV, Q3W and anlotinib 12mg, PO, QD，d1-14, Q3W treatment until disease progression, unacceptable toxicity, or death. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04967625
Study type Interventional
Source Zhejiang Cancer Hospital
Contact Lan Shao
Phone +86 13456964958
Email shaolan28@163.com
Status Not yet recruiting
Phase Phase 2
Start date July 26, 2021
Completion date December 31, 2023
View Details
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