Clinical Study of Comorbidities of Attention Deficit Hyperactivity in Children and Adolescents.

Attention Deficit Hyperactivity Disorder Clinical Trial

Official title:

Clinical Study of Comorbidities of Attention Deficit Hyperactivity in Children and Adolescents.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04946877
• Other study ID #: Comorbidities with ADHD
• Status: Not yet recruiting
• Start date: March 1, 2022
• Est. completion date: October 1, 2022

Study information

• Verified date: February 2022
• Source: Assiut University
• Contact: salma mohmed fahmi, msc
• Phone: 01067151755
• Email: saloma151[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Determine the frequency of psychiatric and neurological comorbidities in children and adolescence diagnosed with ADHD.

Description:

ADHD is a common neurodevelopmental disorder characterized by hyperactivity, impulsivity, and inattention .ADHD is more often a complex disorder with a high rate of associated co-morbid conditions. Co-morbid conditions are prevalent among people with ADHD and increase its burden and complexity of management.Children with ADHD are at a higher risk than children without ADHD for developing other psychiatric disorders .Motor skill problems and Neurological soft signs are found in many neuropsychiatric conditions .NSS have been associated with inattention and behaviour difficulties for decades. Some researchers argue that these signs should be included in the diagnosis of ADHD .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 200
• Est. completion date: October 1, 2022
• Est. primary completion date: August 1, 2022
• Gender: All
• Age group: 6 Years to 17 Years

Eligibility

Inclusion Criteria:

• Age: 6-17 years.

• Sex: both sexes will be included in the study.

• IQ=70.

Exclusion Criteria:

• Age: less than 6 years or more than 17 years.

• IQ<70.

• Patients with major neurological deficits, cerebral palsy and uncontrolled epilepsy.

• Patients with major psychiatric disorders e.g schizophrenia spectrum disorder.

• Patient who refusing to participate in the study or their caregiver refusing to give informed consent.

Related Conditions & MeSH terms

• Attention Deficit Disorder with Hyperactivity
• Attention Deficit Hyperactivity Disorder
• Hyperkinesis

Intervention

Diagnostic Test:
• IQ assessment using Wechsler intelligence scale for children third edition (WISC-III)
IQ assessment using Wechsler intelligence scale for children third edition (WISC-III): is consists of several subtests, each classified into a verbal or performance scale .

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (3)

Faraone SV, Asherson P, Banaschewski T, Biederman J, Buitelaar JK, Ramos-Quiroga JA, Rohde LA, Sonuga-Barke EJ, Tannock R, Franke B. Attention-deficit/hyperactivity disorder. Nat Rev Dis Primers. 2015 Aug 6;1:15020. doi: 10.1038/nrdp.2015.20. Review. — View Citation

Gillberg C, Gillberg IC, Rasmussen P, Kadesjö B, Söderström H, Råstam M, Johnson M, Rothenberger A, Niklasson L. Co-existing disorders in ADHD -- implications for diagnosis and intervention. Eur Child Adolesc Psychiatry. 2004;13 Suppl 1:I80-92. Review. — View Citation

Jensen CM, Steinhausen HC. Comorbid mental disorders in children and adolescents with attention-deficit/hyperactivity disorder in a large nationwide study. Atten Defic Hyperact Disord. 2015 Mar;7(1):27-38. doi: 10.1007/s12402-014-0142-1. Epub 2014 Jun 19. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Determine psychiatric comorbidities in children and adolescents with ADHD using Mini international neuropsychiatric interview for children and adolescents (M.I.N.I. Kid).	Mini international neuropsychiatric interview for children and adolescents (M.I.N.I. Kid): is structured clinical diagnostic interview designed to assess the presence of current ICD-10 and DSM-IV psychiatric disorders in children and adolescents age 6-17 years	baseline
Secondary	determinate presence of soft neurological sign in children and adolescents with ADHD using Cambridge neurological inventory.	Neurological assessment using Cambridge neurological inventory: this is a clinical instrument constructed for standardized neurological assessment of psychiatric patients. It is useful for identifying neurological soft sign and other patterns of neurological impairments	baseline