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Non-gene Edited Anti-CD7 CAR T Cells for Relapsed/Refractory T Cell Malignances

T-cell Acute Lymphoblastic Leukemia Clinical Trial

Official title:
Non-gene Edited Anti-CD7 CAR T Cells for Relapsed/Refractory T Cell Malignances

Clinical Trial Summary

This is a phase I, interventional, single arm, open label, treatment study to evaluate the safety and tolerability of non-gene edited anti-CD7 CAR (also called anti-CD7 CAR) T cells in patients with relapsed and/or refractory T cell lymphoma or leukemia

Clinical Trial Description

Anti-CD7 CAR is a chimeric antigen receptor immunotherapy treatment designed to treat leukemia/lymphoma expressing CD7 antigen. T-cell acute lymphoblastic leukemia, T-acute lymphoblastic lymphoma and T-cell non-Hodgkin lymphoma are a subset of leukemias and lymphomas that are positive for the surface protein CD7. The purpose of this study is to evaluate the efficacy and safety of anti-CD7 CAR T cells. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04934774
Study type Interventional
Source iCell Gene Therapeutics
Contact Kevin Pinz, MS
Phone 6315386218
Email kevin.pinz@icellgene.com
Status Recruiting
Phase Phase 1
Start date December 1, 2020
Completion date June 1, 2023
View Details
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