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A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa

Recessive Dystrophic Epidermolysis Bullosa Clinical Trial

Official title:
Open Label Treatment of Beremagene Geperpavec (B-VEC)

Clinical Trial Summary

This is a 112-week (approximately two-year) open-label extension study of Beremagene Geperpavec (B-VEC), for participants aged 2 months and older, who have been diagnosed with Dystrophic Epidermolysis Bullosa (DEB). Participants will be dosed weekly with the topical B-VEC therapy. The primary endpoint will be to assess long term safety and tolerability of the topical gene therapy. The study is for those who participated in Phase 3 study, as well as, new participants who were unable to participate in the Phase 3 study, who meet all enrollment criteria.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04917874
Study type Interventional
Source Krystal Biotech, Inc.
Contact
Status Completed
Phase Phase 3
Start date May 25, 2021
Completion date July 31, 2023
View Details
See also
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