Caffeine and the Autonomic Nervous System

Autonomic Nervous System Imbalance Clinical Trial

Official title:

Impact of Caffeine Consumption on Markers of the Autonomic Nervous System

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04886869
• Other study ID #: CaffeineLMU
• Status: Recruiting
• Phase: N/A
• Start date: April 1, 2021
• Est. completion date: June 30, 2021

Study information

• Verified date: May 2021
• Source: Klinikum der Universitaet Muenchen
• Contact: Stefan Brunner, MD
• Phone: +49 89 4400 0
• Email: Stefan.Brunner[@]med.uni-muenchen.de
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Caffeine consumption has been linked to dysfunction of the autonomic nervous system. In this study the investigators analyze the effects of caffeine containing drinks (including energy drinks and coffee) on ECG based parameters of the autonomic nervous system.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 20
• Est. completion date: June 30, 2021
• Est. primary completion date: June 30, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• healthy individuals
• > 18 years

Exclusion Criteria:

• known cardiovascular disease
• other diseases which may influence the autonomic nervous system
• medication which may influence the autonomic nervous system
• prior caffeine consumption (<24 hours)

Related Conditions & MeSH terms

• Autonomic Nervous System Imbalance

Intervention

Dietary Supplement:
• caffeine
oral consumption

Locations

Country	Name	City	State
Germany	University Hospital Munich (LMU Klinikum)	Munich

Sponsors (1)

Lead Sponsor	Collaborator
Klinikum der Universitaet Muenchen

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Heart rate (HR)	ECG-based analysis of heart rate (beats per minute)	2 hours
Secondary	Periodic repolarization dynamics (PRD)	ECG-based analysis of repolarization instability (deg²)	2 hours