Sleep Profiles in REM Sleep Behavior Disorder

Rapid Eye Movement Sleep Behavior Disorder Clinical Trial

Official title:
Circadian Rhythms Regulation in Pre-Manifest Synucleinopathies

Status Recruiting

Clinical Trial Summary

Rapid eye movement (REM) sleep behavior disorder (RBD) is a sleep disorder in which you act out dreams during REM sleep. Sleep disturbances are very common in RBD, where they negatively impact patients' quality of life and safety. One of the known causes of sleep disturbance is the impairment of the "circadian rhythm", or the human sleep/wake cycle. The purpose of this study is to examine the role of disruption of the circadian rhythm in the development of RBD.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Mental Disorders
Rapid Eye Movement Sleep Behavior Disorder
REM Sleep Behavior Disorder

Clinical Trial Details

NCT number	NCT04886076
Study type	Observational
Source	Massachusetts General Hospital
Contact	Aleksandar Videnovic, M.D.
Phone	(617) 724-3837
Email	avidenovic@mgh.harvard.edu
Status	Recruiting
Phase
Start date	December 7, 2018
Completion date	December 2021

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04534023` - A Clinical Study of the Efficacy of Idebenone in the Treatment of iRBD Into Synucleinopathies	Phase 2
Terminated	`NCT05307770` - Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder	N/A
Active, not recruiting	`NCT00817726` - RBD Longitudinal as Prognostic for PD
Active, not recruiting	`NCT04020198` - A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies