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Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes

Spinal Cord Injuries Clinical Trial

Official title:
Transcutaneous Spinal Neuromodulation to Normalize Autonomic Phenotypes

Clinical Trial Summary

This study looks to characterize autonomic nervous system dysfunction after spinal cord injury and identify the potential role that transcutaneous spinal cord stimulation may play at altering neuroregulation. The autonomic nervous system plays key parts in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically encounter complications. For both individuals with spinal cord injury and uninjured controls, experiments will utilize multiple parallel recordings to identify how the autonomic nervous system is able to inhibit and activate sympathetic signals. The investigators anticipate that those with autonomic dysfunction after spinal cord injury will exhibit abnormalities in these precise metrics. In both study populations, transcutaneous spinal cord stimulation will be added, testing previously advocated parameters to alter autonomic neuroregulation. In accomplishing this, the investigators hope to give important insights to how the autonomic nervous system works after spinal cord injury and if it's function can be improved utilizing neuromodulation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04858178
Study type Interventional
Source Spaulding Rehabilitation Hospital
Contact
Status Completed
Phase N/A
Start date February 17, 2022
Completion date November 14, 2022
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