Adherence to Oral Anticancer Treatment Clinical Trial
— IMPAMOfficial title:
Impact of a Multidisciplinary Consultation Program on Drug Adherence in First Oral Anticancer Treatment
| NCT number | NCT04797143 |
| Other study ID # | PI2021_843_0023 |
| Secondary ID | |
| Status | Recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | March 11, 2021 |
| Est. completion date | March 2024 |
Oncology management has changed dramatically over the last decade with the approval and rapid adoption of newly targeted oral oncology medications. The movement to oral oncology medications has altered the balance of risks and adverse effects (AEs) in the treatment of cancer care. These treatments are associated with a different constellation of AEs and drug interactions. Patients receiving treatment with oral anticancer treatment (OAT) encounter several barriers to adherence, which may include limited access to specialty medications, severe adverse effects, complex medication regimens, and special handling precautions. Medication nonadherence not only reduces the efficacy of drug therapy but also has the potential to increase healthcare expenditures due to disease-related hospitalizations. The purpose of this study is to evaluate the drug adherence in cancer patients, using the medication possession ratio (MPR), before and after the implementation of a multidisciplinary consultation program (MCP), on initiation of OAT.
| Status | Recruiting |
| Enrollment | 300 |
| Est. completion date | March 2024 |
| Est. primary completion date | March 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - French speaking patients with a newly diagnosed or relapsed cancer, regardless of location and introduction of oral anticancer treatment Exclusion Criteria: - patients treated with hormone therapy only - Patient with severe psychiatric disorders - patient who does not speak the French language |
| Country | Name | City | State |
|---|---|---|---|
| France | CHU Amiens | Amiens |
| Lead Sponsor | Collaborator |
|---|---|
| Centre Hospitalier Universitaire, Amiens |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | medication possession ratio (MPR) | The MPR makes it possible to determine the percentage of days of treatment covered by pharmacy dispensing. A patient is generally considered observant if MPR is greater than or equal to 80%. | two months | |
| Primary | medication possession ratio (MPR) | The MPR makes it possible to determine the percentage of days of treatment covered by pharmacy dispensing. A patient is generally considered observant if MPR is greater than or equal to 80%. | one year |