Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension

Post-spinal Anesthesia Hypotension Clinical Trial

Official title:

Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension in Patients Undergoing Orthopedic Surgeries

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04780139
• Other study ID #: FMASU R 25/2020/2021
• Status: Completed
• Start date: March 1, 2021
• Est. completion date: July 21, 2021

Study information

• Verified date: July 2021
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.

Description:

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH. Spinal anaesthesia is frequently used in daily clinical practice. Postspinal anaesthesia hypotension (PSAH) is a common side effect with an incidence of 15.3 to 33% that may result in organ hypoperfusion and ischaemic events. Patients' susceptibility to intraoperative hypotension can be influenced by the sensory block level, age, preoperative volume status , physical status, pre-operative medications and fasting.

PSAH due to spinal blockade is principally a consequence of diminished systemic vascular resistance after blockade of preganglionic sympathetic fibres. Many attempts have been tried to prevent PSAH, such as intravenous volume preload or prophylactic vasopressors. However, fluid infusion has been proved to lower the incidence of PSAH and significantly decrease vasopressor requirements. At the same time, empirical volume loading carries the potential of volume overload, particularly in patients with cardiac disease. Consequently, the search for predictors of PSAH is becoming mandatory to avoid blind volume loading and reserve it only for patients who are expected to develop PSAH. .

.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 62
• Est. completion date: July 21, 2021
• Est. primary completion date: July 21, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 40 Years and older

Eligibility

Inclusion Criteria:

• patients more than 40 years of age.

• American Society of Anesthesiologists' (ASA) physical status 1 or 2.

• scheduled for elective surgery under spinal anaesthesia in the supine position.

Exclusion Criteria:

• BMI more than 35 kg m2.

• taking angiotensin converting enzyme inhibitors.

• pregnant women.

• emergency cases.

• absolute or relative contraindications to spinal anaesthesia.

• Also, patients with a baseline arterial systolic blood pressure less than 90 mmHg or mean arterial blood pressure (MBP) less than 70 mmHg will be excluded.

Related Conditions & MeSH terms

• Hypotension
• Post-spinal Anesthesia Hypotension

Intervention

Diagnostic Test:
• Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area
Measuring the internal jugular vein cross section area and relate this to the incidence of hypotension after spinal anesthesia.

Locations

Country	Name	City	State
Egypt	Ain Shams University hospital	Cairo	???????

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Predictive value of internal jugular vein (IJV) cross sectional area.	The primary outcome is to evaluate the predictive value of internal jugular diameter cross sectional area for detecting PSAH	30 minutes