Nigella Sativa Oil Extract and Xenograft Bone Graft in Treatment of Infra-bony Defects

Localized Aggressive Periodontitis Clinical Trial

Official title: Nigella Sativa Oil Extract and Xenograft Bone Graft in Treatment of Infra-bony Defects: a Combined Clinical and Histological Study

Status Active, not recruiting

Clinical Trial Summary

The aim of this study will be to evaluate, clinically, and radiographically the effect of Nigella Sativa oil extract Mixed with xenograft versus xenograft alone in the treatment of intra-bony defects in patients with aggressive periodontitis.

Clinical Trial Description

in 10 patients, twenty sites in subjects with, localized aggressive periodontitis, with CAL ≥ 5 will be included in the present study. Sites will be allocated randomly to be surgically treated with, Nigella Sativa oil extract Mixed with xenograft or xenograft alone. At baseline, 3, 6 after surgery, the following clinical parameters (PD, CAL, BOP) and CBCT at baseline and 6 months x-ray will be recorded. ;

Related Conditions & MeSH terms

• Aggression
• Aggressive Periodontitis
• Localized Aggressive Periodontitis
• Periodontitis

• NCT number: NCT04722380
• Study type: Interventional
• Source: Tanta University
• Status: Active, not recruiting
• Phase: Phase 2
• Start date: October 1, 2020
• Completion date: December 1, 2021