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Clinical Trial Summary

This is a multicenter screening protocol designed to identify patients with NSCLC who have tumor mutations in the KEAP1 or NRF2/NFE2L2 genes in order to determine potential eligibility for a biomarker selected clinical trial (CX-839-014, otherwise known as the KEAPSAKE trial). Circulating tumor DNA (ctDNA) present in blood samples collected from eligible patients will be analyzed by next generation sequencing (NGS) for selected biomarkers. A commercial liquid biopsy NGS test will be provided to study participants free of charge.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04698681
Study type Observational
Source Calithera Biosciences, Inc
Contact
Status Terminated
Phase
Start date January 19, 2021
Completion date February 9, 2022

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