Refractory B-Cell Non-Hodgkin Lymphoma Clinical Trial
Official title:
Phase I, Open Label, Study of CXCR4 Modified CD19 CAR-T Therapy in Patients With Relapsed or Refractory CD19+ B-cell Malignancies
This study aims to evaluate the safety and tolerance of modified CD19 CAR T cells in treating refractory/relapsed B-cell malignancies. CAR-T cells will be investigated as a single agent both in relapsed/refractory B-cell acute lymphoblastic leukaemia (B-ALL) and up to 60% of patients with B-cell non-Hodgkin's lymphoma (NHL).
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|---|---|---|---|
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Phase 1 | |
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Phase 1/Phase 2 | |
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Phase 1 | |
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Phase 2 | |
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Phase 1 |