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The Role of Mucosal Microbiome in the Development, Clearance and Recurrence of Clostridioides Difficile Infection

Clostridioides Difficile Infection Clinical Trial

Official title:
The Role of Mucosal Microbiome in the Development, Clearance and Recurrence of Clostridiodes Difficile Infection

Clinical Trial Summary

The study is being done to identify types of bacteria associated with the lining of the large intestine in people who have recently been diagnosed with C. difficile infection to determine if there are features associated with development, clearance, and recurrence of disease.

Clinical Trial Description

Patients who were recently diagnosed with C. difficile infection will undergo assessment of both before treatment and after completing treatment to study the presence of C. difficile in the colonic mucosa pre as well as assessment for microbiome and patient/clinical factors that may contribute to disease recurrence. Assessment will include sigmoid colon biopsies, blood draw, stool samples and surveys. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04679324
Study type Observational
Source Mayo Clinic
Contact
Status Withdrawn
Phase
Start date September 23, 2019
Completion date August 10, 2022
View Details
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