Clinical Trials Logo

Clinical Trial Summary

Social functioning deficits are among the most disabling and difficult to treat aspects of schizophrenia. An essential component of social functioning is metacognition-a process that is profoundly disrupted in schizophrenia and represents the ability to reflect upon the mental states of oneself and others. To date, treatment efforts in schizophrenia have been hindered by barriers in accurately monitoring client's real-world social interactions. Recently, wearable technologies have evolved to provide therapists with innovative, ecologically-valid tools. The Electronically Activated Recorder is a wearable audio recorder that collects behavioral samples at pre-programmed intervals; it holds great promise as a method for yielding concrete, real-world examples of social interactions that can be used by therapists in session to enhance metacognition. Despite the immense costs of social functioning deficits, no previous studies have investigated whether functioning can be improved by integrating wearable audio recorders with psychosocial interventions. By enhancing therapy using a wearable recording device, this proposal's primary goal is to implement a novel intervention that targets metacognitive deficits to improve social functioning. The novel intervention will be tailored to individual clients-based on the content of recorded social interactions-in a way that is not possible using traditional psychotherapy. This will allow clients and therapists to step out of the therapy room by offering a window into how clients process material in real-world interactions. In this study, a randomized controlled trial will be conducted with two schizophrenia groups receiving six months of individualized: 1) Metacognition Reflection and Insight Therapy (MERIT) alone (Standard MERIT); and 2) Tailored MERIT using wearable audio recorders. In this study, our specific aims will test feasibility, effectiveness, and acceptability of Tailored MERIT.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04665401
Study type Interventional
Source Indiana University
Contact
Status Completed
Phase N/A
Start date July 1, 2016
Completion date March 15, 2020

See also
  Status Clinical Trial Phase
Completed NCT05321602 - Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder Phase 1
Recruiting NCT04298450 - ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention N/A
Enrolling by invitation NCT03090490 - 10-year Follow-up of Clinical Outcome After Antipsychotic Treatment Discontinuation in Psychosis Individuals N/A
Completed NCT03323437 - Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia Phase 4
Recruiting NCT06423651 - Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum Disorders N/A
Completed NCT06040944 - Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients
Recruiting NCT04452175 - Cigarette Consumption After switchinG to High or Low Nicotine strENght E-cigaretteS In Smokers With Schizophrenia N/A
Completed NCT03501888 - Cognitive Behavior Therapy for Patients With Psychoses. N/A
Completed NCT05601063 - Ascertaining Diagnosis Classification With Elicited Speech
Recruiting NCT05877716 - EPI-MINN: Targeting Cognition and Motivation - National N/A
Completed NCT03955549 - Insight Enhancement Program vs. Metacognitive Training for Psychosis in Patients With Schizophrenia: A Three-Armed Comparative Randomized Controlled Trial Phase 3
Completed NCT03235908 - Copeptin in Outcome Prediction of an Acute Psychotic Episode
Recruiting NCT05622201 - A Randomized Controlled Trial With Rituximab for Psychotic Disorder in Adults Phase 2
Recruiting NCT05491486 - Mindfulness, Empathy and the Oxytocinergic System in Persons With Schizophrenia N/A
Completed NCT04916496 - Acceptance and Commitment Therapy-based Lifestyle Counselling Programme for Early Psychosis on Physical Activity N/A
Recruiting NCT04104347 - Metacognitive Training and Insight in Schizophrenia N/A
Recruiting NCT05664594 - State Representation in Early Psychosis - Project 4 N/A
Recruiting NCT05538832 - Remote State Representation in Early Psychosis Early Phase 1
Completed NCT02220504 - 3-year Follow-up of Clinical Outcome After Antipsychotic Treatment Discontinuation in Psychosis Individuals N/A
Recruiting NCT03919760 - Early Psychosis Intervention - Spreading Evidence-based Treatment