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CAR-T for Children With Relapsed and Refractory Acute Lymphoblastic Leukemia

Childhood Acute Lymphoblastic Leukemia Clinical Trial

Official title:
An Open, Uncontrolled, Multicenter Clinical Trial to Explore the Safety, Efficacy, and Remission Phase of Chimeric Antigen Receptor T Cell (CAR-T) in the Treatment of Children With Relapsed and Refractory Acute Lymphoblastic Leukemia

Clinical Trial Summary

In this study, CAR-T will be administered to children with acute lymphoblastic leukemia to explore the effect of CAR-T intervention time on the duration of complete remission and further verify the long-term safety and efficacy of CAR-T treatment.

Clinical Trial Description

After clinician evaluation, if the child meets the study criteria and after adequate communication, the parent or legal guardian voluntarily joins the clinical study, CAR-T technique can be used for related treatment, and the long-term therapeutic effect can be observed. In this trial, 50 children were publicly enrolled and treated with CAR-T. Patients participating in the clinical trial will be tested and assessed in terms of treatment safety, efficacy, and duration of response. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04626765
Study type Interventional
Source Hebei Senlang Biotechnology Inc., Ltd.
Contact Jianqiang Li, PhD&MD
Phone +8631189928689
Email limmune@gmail.com
Status Recruiting
Phase Early Phase 1
Start date April 1, 2020
Completion date May 30, 2023
View Details
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