Edentulous; Alveolar Process, Atrophy Clinical Trial
Official title:
Evaluation of Melatonin and Hyaluronic Acid in Maxillary Sinus Augmentation (a Randomized Controlled Clinical Trial)
Verified date | December 2020 |
Source | Alexandria University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
melatonin proved an ability to repair bone defects and enhance osseointegration of dental implants. Also, hyaluronic acid has osteopromoting properties. the effect of melatonin and hyaluronic acid on the newly formed bone in maxillary sinus augmentation was evaluated
Status | Completed |
Enrollment | 16 |
Est. completion date | December 7, 2020 |
Est. primary completion date | December 7, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 30 Years to 50 Years |
Eligibility | Inclusion Criteria: - Age range will be between (30 - 50) years old. - Patients with missed one or more of posterior teeth with minimum residual bone height 5 mm - Adequate inter-occlusal space of at least 8 mm Exclusion Criteria: - Maxillary sinus diseases. - Previous sinus surgery like the Caldwell-Luc operation. - History of chemotherapy or radiotherapy to maxilla. - Presence of Underwood's septa/severe sinus floor convolutions. - Systemic disease affecting bone metabolism. - Uncontrolled diabetes mellitus. - Heavy smokers. - Para functional habits. |
Country | Name | City | State |
---|---|---|---|
Egypt | Faculty of Dentistry, Alexandria University | Alexandria |
Lead Sponsor | Collaborator |
---|---|
Hams Hamed Abdelrahman |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | change Implant stability | The result is presented as an ISQ value of 1-100. The acceptable stability range lies between 55-85 ISQ. The higher the ISQ, the more stable the implant | at baseline and 6 months | |
Primary | change in bone density | radiographical evaluation using CBCT | at baseline, 1 month and 6 months | |
Primary | change in vertical bone height | radiographical evaluation using CBCT | at baseline, 1 month and 6 months | |
Primary | change in marginal bone level | radiographical evaluation using CBCT | at baseline, 1 month and 6 months | |
Secondary | Postoperative pain | based on a 4-point verbal descriptive scale as following: no pain, mild (recognizable but not discomforting pain that required no analgesics), moderate (discomforting but bearable pain and analgesics if used were effective in relieving pain) and severe (difficult to bear and analgesics were effective in relieving pain). | after 1 week | |
Secondary | Postoperative swelling | none (no inflammation), mild (intraoral swelling confined to the surgical field), moderate (extraoral swelling in the surgical zone) and severe (extraoral swelling spreading beyond the surgical zone). | after 1 week |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05410405 -
Osseodensification Drills Versus Piezoelectric Surgery
|
N/A | |
Not yet recruiting |
NCT05108324 -
Reliability of All on 4 Using 2 Zygomatic and 2 Conventional Implants vs All on 4 Implants for Rehabilitation of Maxilla
|
N/A | |
Completed |
NCT03401554 -
Titanium Mesh Versus Collagen Membrane for Closure of Window in Maxillary Sinus Elevation With Implant Placement
|
N/A | |
Completed |
NCT05284461 -
Effect of Shape and Surface Treatment of the Transmucosal Abutments on Peri-implant Health.
|
N/A | |
Active, not recruiting |
NCT03495700 -
Lateral Sinus Floor Elevation in Implant Therapy.
|
N/A | |
Active, not recruiting |
NCT03496038 -
Transcrestal Lateral Sinus Floor Elevation in Implant Therapy
|
N/A | |
Completed |
NCT04017156 -
Bone Healing at Non-submerged Implants Installed With Different Insertion Torques.
|
N/A | |
Completed |
NCT04136509 -
Microarchitecture of the Augmented Bone Following Sinus Elevation
|
N/A | |
Completed |
NCT05500911 -
Bioactive Surfaces vs. Conventional Surfaces in Implants Placed in Atrophic Maxilla With Simultaneous Sinus Lift
|
N/A |