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NCT04567056 Clinical Trial

Specific Methylation Profiles in HNSCC

Head and Neck Squamous Cell Carcinoma Clinical Trial

Official title:
Validation of Specific Methylation Profiles Ind Head and Neck Cancer - A Cohort Study

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04567056
Other study ID # N-20190047-2
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date September 16, 2020
Est. completion date December 20, 2024

Study information
Verified date February 2024
Source Aalborg University Hospital
Contact Christian Danstrup, M.D.
Phone +45 23800598
Email csd@rn.dk
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In the study, N-20190047, the investigators aim to define specific methylation patterns in a group of patients with head and neck squamous cell carcinomas. With this study the investigators aim to validate these findings in a larger cohort.

Recruitment information / eligibility
Status Recruiting
Enrollment 300
Est. completion date December 20, 2024
Est. primary completion date October 1, 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Cancer group: Inclusion Criteria: - Written informed consent - Verified head and neck squamous cell carcinoma Exclusion Criteria: - Other active cancer - Uncontrolled comorbidity - Unable to give informed consent Control group: Inclusion Criteria: - Written informed consent - Normal ENT-examination Exclusion Criteria: - Other active cancer - Uncontrolled comorbidity - Unable to give informed consent

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Blood sample
A separate blood sample will be taken for methylation-analyses

Locations
Country Name City State
Denmark Department of Otolaryngology - Head and Neck Surgery Aalborg

Sponsors (1)
Lead Sponsor Collaborator
Aalborg University Hospital

Country where clinical trial is conducted

Denmark, 

Outcome
Type Measure Description Time frame Safety issue
Primary Diagnostic accuracy How accurate can the methylation profiles diagnose the head and neck squamous cell carcinoma At diagnosis
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