A Model for Risk Prediction of Fracture in Diabetic Patients With Osteoporosis

Healthcare; Risk Prediction; Diabetic Patients With Osteoporosis Clinical Trial

Official title:

A Model for Risk Prediction of Fracture in Diabetic Patients With Osteoporosis

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT04534166
• Other study ID #: XH-20-020
• Status: Enrolling by invitation
• Start date: July 1, 2012
• Est. completion date: September 30, 2022

Study information

• Verified date: August 2020
• Source: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The fracture risk of diabetic patients proves to be higher than those without diabetesdue to thehyperglycemia, usage of diabetes drugs, the changes in insulin levels and excretion, and this risk begins as early as adolescence.Many factors may be related to bone metabolism in patients with diabetes, including demographic data (e.g. age, height, weight, gender), medical history (e.g. smoking, drinking, menopause) and examination (e.g. bone mineral density, blood routine), urine routine).However, most of existing methods are qualitative assessments and do not take the interactions of the physiological factors of humans into consideration. In addition, the fracture risk of diabetic patients with osteoporosis has not been further studied before. In order to investigate the effect of patients' physiological factors on fracture risk, in the paper, we used a hybrid model combining XGBoost with deep neural network to predict the fracture risk of diabetic patients with osteoporosis.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 0
• Est. completion date: September 30, 2022
• Est. primary completion date: September 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients in Hospital's outpatient and inpatient His database between July 2012 and November 2022, diabetic patients were combined with osteoporosis.

Exclusion Criteria:

• Patients with fractures before diagnosis of diabetes; patients with fractures before diagnosis of osteoporosis; patients with hyroid disease and other diseases that seriously affect bone metabolism.

Related Conditions & MeSH terms

• Healthcare; Risk Prediction; Diabetic Patients With Osteoporosis
• Osteoporosis

Intervention

Other:
• Risk Prediction of Fracture in Diabetic Patients with Osteoporosis
Risk Prediction of Fracture in Diabetic Patients with Osteoporosis

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Fracture		2-10 year