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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT04493112
Other study ID # Sequent Please NEO
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 5, 2018
Est. completion date December 31, 2021

Study information

Verified date July 2020
Source Germans Trias i Pujol Hospital
Contact Oriol Rodriguez, MD, PhD
Phone +34 93 497 89 89
Email Oriol.Rodriguez@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The registry evaluates the safety and efficacy of paclitaxel-releasing SeQuent® Please Neo balloon in the following scenarios: restenosis, bifurcation lesions, small vessel lesions, diabetes (diffuse disease) and atrial fibrillation. The objective is to determine the success of the procedure and the preservation of vascular permeability.


Description:

The preset registry aim is to evaluate the safety and efficacy of paclitaxel-releasing SeQuent® Please Neo balloon in the following scenarios: restenosis, bifurcation lesions, small vessel lesions, diabetes (diffuse disease) and atrial fibrillation. The principal objective is to determine the success of the procedure and the preservation of vascular permeability.


Recruitment information / eligibility

Status Recruiting
Enrollment 1000
Est. completion date December 31, 2021
Est. primary completion date December 31, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- ISR in a coronary artery with a diameter stenosis of at least 70%, a length of the stented segment of <25 mm, and a vascular diameter of at least 2.5 and up to 3.5 mm

Exclusion Criteria:

- There is no exclusion criteria except those patients with contraindication for antiplatelet therapy.

Study Design


Related Conditions & MeSH terms

  • Drug Coating Balloon (DCB), Sequent Please

Locations

Country Name City State
Spain Hospital Universitari Germans Trias i Pujol Badalona Barcelona

Sponsors (1)

Lead Sponsor Collaborator
Germans Trias i Pujol Hospital

Country where clinical trial is conducted

Spain, 

Outcome

Type Measure Description Time frame Safety issue
Primary Target Lesion Revascularization (TLR) with clinical follow-up at 12 months. Target Lesion Revascularization (TLR) with clinical follow-up at 12 months. From baseline to 12 months
Secondary Success of balloon dilation. Success of balloon dilation. Baseline
Secondary Acute adverse cardiac events rate (MACE) and and MACE rate accumulated at 12 months. MACE rate and MACE rate accumulated at 12 months. From baseline to 12 months
Secondary Premature follow-up indication Premature follow-up indication From baseline to 12 months