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Outcome of Patients With Primary Aldosteronism — PA_Outcome  

Primary Aldosteronism Clinical Trial

Official title:
Long-term Outcomes in Patients With Primary Aldosteronism After Treatment

Clinical Trial Summary

Majority of patients with hypertension have primary hypertension (without an underlying cause). Primary aldosteronism (PA) is the most common cause of secondary hypertension, and can be found in 5-10% of patients locally. PA is caused by excessive release of a hormone (aldosterone) from the adrenal glands, which can be unilateral (one gland) or bilateral (both glands). It has been shown that excess aldosterone has other harmful effects in addition to hypertension, such as directly affecting the heart, blood vessels, kidneys, leading to increased cardiovascular morbidity and mortality. This is supported by studies showing reversal of these effects after treatment for PA. The investigators aim to assess the long-term cardiovascular, and renal outcomes of patients with PA, compared to patients with essential hypertension.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04428827
Study type Observational
Source Changi General Hospital
Contact Troy Puar, MRCP
Phone 67888833
Email troy_puar@cgh.com.sg
Status Recruiting
Phase
Start date October 1, 2016
Completion date July 30, 2022
View Details
See also
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