Siewert Type II Adenocarcinoma of Esophagogastric Junction Clinical Trial
Official title:
A Prospective Clinical Study of Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert Type Ⅱ Adenocarcinoma of Esophagogastric Junction
Objective: To evaluate the safety, feasibility and clinical efficacy of transthoracic
single-hole assisted laparoscopic radical gastrectomy for Siewert Type Ⅱ adenocarcinoma of
esophagogastric junction.
Methods: A prospective, single-center, one-arm study will be performed. Patients who have
been diagnosed with Siewert type Ⅱ esophagogastric junction adenocarcinoma and meet the
eligibility criteria will be included in the study and undergo the transthoracic single-hole
assisted laparoscopic radical gastrectomy. The data of preoperative, intraoperative,
postoperative and follow-up will be recorded and analyzed.
Primary study endpoints: The incidences of early postoperative complications and mortality.
The secondary study endpoints:(1) Surgery and oncology indicators ;(2) Early postoperative
recovery information ;(3) 3-year disease-free survival and overall survival rate;(4) 5-year
disease-free survival and overall survival.
1. Surgery and oncology indicators,such as length of operation, intraoperative blood loss,
transit thoracotomy or laparotomy rate, length of proximal tumor from esophageal
resection margin, number of mediastinal lymph node dissections and the positive, number
of abdominal lymph node dissections and the positive, tumor type and pathological stage,
etc.;
2. Early postoperative recovery information ,such as time of first exhaust and defecation,
time of leaving the bed, time of recovery of full and half-flow diet, time of removal of
chest drainage tube, time of postoperative hospitalization, etc.
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