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Clinical Trial Summary

TC-110 T cells are a novel cell therapy that consists of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human CD19, fused to the CD3-epsilon subunit which, upon expression, is incorporated into the endogenous T cell receptor (TCR) complex. This is a Phase 1/2 open-label study to evaluate the safety of autologous genetically engineered TC-110 T cells in patients with aggressive NHL (DLBCL, PMBCL, TFL), high-risk indolent NHL (including MCL), or adult ALL.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04323657
Study type Interventional
Source TCR2 Therapeutics
Contact
Status Completed
Phase Phase 1/Phase 2
Start date March 27, 2020
Completion date February 24, 2023

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