OCT Guided Punctal Stenosis Management

Epiphora Due to Insufficient Drainage Clinical Trial

Official title:

The Role of Anterior Segment Optical Coherence Tomography in Management of Acquired Punctal Stenosis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04318652
• Other study ID #: 32399/09/18
• Status: Completed
• Phase: Phase 4
• Start date: September 2, 2018
• Est. completion date: September 20, 2019

Study information

• Verified date: March 2020
• Source: Tanta University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This is a clinical trial study that was conducted on patients with punctal stenosis.We studied the diameter of stenosed puncta before and after treatment with preserved free steroid eye drops using AS-OCT.

Description:

The study was conducted on 40 eyes of 24 patients have acquired inflammatory punctal stenosis and 20 eyes of 10 patients of normal asymptomatic subjects as control group. We studied the external punctal diameter, visibility of the internal punctum and punctal depth before treatment using AS-OCT, and then patients were re-evaluated after one month of treatment with preservative free methylprednisolone 5% eye drops.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: September 20, 2019
• Est. primary completion date: September 5, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients have acquired inflammatory punctum stenosis complaining of epiphora of different etiologies.

Exclusion Criteria:

• Previous lacrimal surgery.

• Lid margin malposition such as ectropion, entropion or lid retraction.

• Medial lid masses obscuring punctum.

• History of ocular trauma involving lid margin or punctum.

Related Conditions & MeSH terms

• Epiphora Due to Insufficient Drainage
• Lacrimal Apparatus Diseases

Intervention

Drug:
• Methylprednisolone eyedrops
instillation of methylprednisolone eye drops

Locations

Country	Name	City	State
Egypt	Amr Awara	Tanta	Gharbeyia

Sponsors (1)

Lead Sponsor	Collaborator
Tanta University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	punctal opening	evaluation of punctalopening by OCT	one month