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Clinical Trial Summary

The use of Allosure to identify and quantify circulating donor-derived cell-free DNA to quantitate allograft injury in the early post-transplant period and determine its relationship to allograft failure.


Clinical Trial Description

Single Center Prospective Cohort Study on De-Novo Lung Transplant recipients. AlloSure will be drawn as part of routine blood draws and sent to CareDx for analysis of dd-cfDNA. All data will be collected and stored in the hospital EMR, this will be examined with the AlloSure results to correlate outcomes. ;


Study Design


Related Conditions & MeSH terms

  • Lung Transplant Failure and Rejection

NCT number NCT04318587
Study type Interventional
Source University of Pittsburgh
Contact
Status Terminated
Phase N/A
Start date June 29, 2020
Completion date December 30, 2023

See also
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Terminated NCT04558333 - CLAD: Finding Biomarkers to Predict Rejection and/ or Outcome After Lung Transplantation
Recruiting NCT05006742 - Comparison of Transbronchial Cryobiopsy and Forceps Biopsy in Lung Transplant Recipients N/A
Active, not recruiting NCT03656926 - Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-2) Phase 3
Recruiting NCT04837339 - Diagnostic and Prognostic Biomarkers of Transplant Dysfunction in the Context of Lung Transplantation N/A
Enrolling by invitation NCT04787822 - Long Term Follow up of the LTOG Cohort
Enrolling by invitation NCT05934617 - Trajectories of FEV1 After Lung Transplantation
Active, not recruiting NCT04126746 - Clinical Trials in Organ Transplantation Extension Study
Active, not recruiting NCT03657342 - Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) Phase 3