Midazolam in Preeclamptic Patients Clinical Trial
Official title:
Impact of Adding Midzolam to Bupavicaine 0.5% in Regional Spinal Anaesthesia on Maternal Middle Cerebral Artery Velocimetry in Parturients With Severer Preeclampsia
| Verified date | February 2020 |
| Source | Minia University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
Trial to use GABA mimetic action of midazolam to ameliorate the severe preeclampsia induced neuronal excitotoxicity using middle cerebral artery transcranial doppler resisitive vasculer indices to evaluate . Secondery goal is to study end organ injury
| Status | Recruiting |
| Enrollment | 100 |
| Est. completion date | April 5, 2020 |
| Est. primary completion date | February 17, 2020 |
| Accepts healthy volunteers | No |
| Gender | Female |
| Age group | 20 Years to 40 Years |
| Eligibility |
Inclusion Criteria: - All parturients with severe preeclampsia for urgent C.S Exclusion Criteria: - Ladies refusal to participate. Refusal to have spinal anesthsia |
| Country | Name | City | State |
|---|---|---|---|
| Egypt | Elminia university | Cairo |
| Lead Sponsor | Collaborator |
|---|---|
| Minia University |
Egypt,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Measuring Pulsatality index and resistive index of maternal middle cerebral artery | Resistive vasculer indices outcome after intrthecal midazolam injection | 2 months |