Analysis of Biomarkers in Lymph Node Tissue

Analysis of Biomarkers in Lymph Node Tissue Clinical Trial

Official title:

Analysis of Biomarkers in Lymph Node Tissue

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT04228796
• Other study ID #: 19-011883
• Status: Active, not recruiting
• Start date: January 6, 2020
• Est. completion date: January 2027

Study information

• Verified date: March 2024
• Source: Mayo Clinic
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Researchers are doing an exploratory analysis of biomarkers to correlate with treatment outcome of transplant surgery.

Description:

Researchers will study previously collected tissue, which was sent for pathological examination, of 200 patients who underwent transplant surgery. Concentration of biomarkers in lymph node tissue will be measured.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 200
• Est. completion date: January 2027
• Est. primary completion date: January 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adults (18+years of age)

• Undergo any organ transplant

Exclusion Criteria:

• Under the age of 18 years old

Related Conditions & MeSH terms

• Analysis of Biomarkers in Lymph Node Tissue

Locations

Country	Name	City	State
United States	Mayo Clinic in Florida	Jacksonville	Florida

Sponsors (1)

Lead Sponsor	Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	List of biomarkers	Immunohistochemistry (IHC) for the LYVE1, VEGFR3 expression, VEGF-A/C/D, Ki-67, MMP-9 and TIMP-1	Baseline