Anabolic Response to Mycoprotein and Micronutrient Ingeston Clinical Trial
— PIMPOfficial title:
Comparing the Muscle Protein Synthetic Response to Ingestion of Mycoprotein vs Protein Isolated From Mycoprotein
| Verified date | May 2022 |
| Source | University of Exeter |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
Dietary protein is vital for the preservation of health and optimal adaptation to training. However, traditional animal proteins come with a number of economic, environmental, and ethical issues. Accordingly, there is a need to develop an understanding of the utility of more sustainable non-animal derived dietary proteins to support our nutrition. Mycoprotein, produced by Quorn Foods™, has recently been shown to stimulate a greater anabolic response within skeletal muscle compared with milk protein, suggesting its utility within sports nutrition. However, it is unclear what accounted for the greater anabolic response of mycoprotein. One explanation could be the non-protein nutrients contained within mycoprotein (e.g. fibre, carbohydrate, fat or micronutrients). Therefore, the present study will compare the muscle anabolic response between mycoprotein (MYC) as a whole food and the protein isolated from mycoprotein (PIM).
| Status | Completed |
| Enrollment | 24 |
| Est. completion date | December 11, 2019 |
| Est. primary completion date | December 11, 2019 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Male |
| Age group | 18 Years to 40 Years |
| Eligibility | Inclusion Criteria: - BMI between 18 and 30. - Resistance trained Exclusion Criteria: - Any metabolic impairments. - Cardio/pulmonary diseases. - Chronic use of over the counter pharmaceuticals - A personal or family history of epilepsy, seizures or schizophrenia. - Allergic to mycoprotein/Quorn/edible fungi/environmental mould products. |
| Country | Name | City | State |
|---|---|---|---|
| United Kingdom | University of Exeter | Exeter |
| Lead Sponsor | Collaborator |
|---|---|
| University of Exeter | Quorn |
United Kingdom,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Muscle protein synthesis | The rate of synthesis of new muscle protein (Fractional Synthetic Rate %/h) | 7.5 hours | |
| Secondary | Plasma Amino Acid Kinetics | The rate of appearance of amino acids ingested in the drink | 7.5 hours | |
| Secondary | Blood Glucose | The levels of glucose in the blood | 7.5 hours | |
| Secondary | Serum Insulin | The levels of insulin in blood serum | 7.5 hours |