Serum and Urine Titanium Levels in Children With Early Onset Scoliosis Treated With Growth-Sparing Instrumentation

Early-Onset Scoliosis Deformity of Spine Clinical Trial

Official title: Serum and Urine Titanium Levels in Children With Early Onset Scoliosis Treated With Growth-Sparing Instrumentation

Status Completed

Clinical Trial Summary

The investigators are conducting research to compare serum and urine titanium levels in children with early onset scoliosis who are being treated with certain types of metal spinal rods. These rods include traditional growing rods (TGR), magnetically-controlled growing rods (MCGR), and Vertical Expandable Prosthetic Titanium Rib (VEPTR). Children with metal rods may have elevated serum and urine titanium levels. These levels may remain elevated over time. The investigators will collect serum titanium levels from children with metal rods and children without metal rods to see if there are differences in their titanium levels. The investigators will then collect a second serum titanium level from children with metal rods at least 6 months later to see if the participants titanium levels remain elevated over time. The investigators will also collect urine titanium levels from children with metal rods to see if titanium is excreted in the urine.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Early-Onset Scoliosis Deformity of Spine
• Scoliosis

• NCT number: NCT04069637
• Study type: Observational [Patient Registry]
• Source: University of Michigan
• Status: Completed
• Start date: November 7, 2019
• Completion date: July 19, 2022