Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant

Donor to Recipient Gender Mismatch in LDLT Clinical Trial

Official title:

Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant: A Single Centre Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04068363
• Other study ID #: IBR/0006379
• Status: Completed
• Start date: August 15, 2019
• Est. completion date: June 20, 2021

Study information

• Verified date: February 2022
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Liver transplantation (LT) represents the gold-standard therapy for the treatment in case of dreadful liver pathologies . It is thus a main concern to optimize the results in terms of post-LT survivals. The effect of gender match on post-transplant outcome is still debatable. Hormonal , and size difference between female and male may be proposed to affect the post transplant outcome . The aim of this study is to evaluate the effect of donor-recipient gender mismatch on survival rates

Recruitment information / eligibility

• Status: Completed
• Enrollment: 342
• Est. completion date: June 20, 2021
• Est. primary completion date: March 15, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult Egyptian Patients >18 years.

Exclusion Criteria:

• Patient refusal.

• Patients who underwent re-transplantation before discharge from the ICU after the first liver transplant.

• Intraoperative cardiac arrest or immediately postoperative cardiac arrest within the first 6 hours postoperative.

• Massive blood loss.

• Pre-existing renal failure requiring hemodialysis or continuous hemofiltration.

• Pregnancy.

Related Conditions & MeSH terms

• Donor to Recipient Gender Mismatch in LDLT

Intervention

Other:
• non interventional
non interventional study

Locations

Country	Name	City	State
Egypt	Hanaa El Gendy	Cairo	Ain Shams University Specialized Hospital

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	2 years survival post liver transplant.	The primary outcome will be survival at 2 years post liver transplant	3 months