Fluid Resuscitation Monitoring Non-invasively Clinical Trial
Official title:
The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study
Recently, bedside ultrasound has become an important tool for the simple and non-invasive
hemodynamic assessment of critically ill patients. This applies not only to echocardiography
but also to ultrasound of large extra-thoracic veins. The sonography can provide real time
assessment of the vascular system and hemodynamic status at the bedside.
To our knowledge, there is one report about the association between sonographically assessed
carotid artery diameter and intravascular volume, which raised recommendation for further
studies including the interplay between carotid geometry and intravascular fluid status.
Aim of the study:
The aim of this work is to evaluate the accuracy of noninvasive techniques for assessment of
intravascular volume status by Sonographic assessment of both the common carotid artery
diameter (CCA) and the central venous pressure (CVP) in response to a bolus of crystalloid
solution infusion and to find the correlation between CCA diameter and CVP as the primary
outcome in adults patients after major surgeries who needs close assessment and maintenance
of the intravascular volume status.
| Status | Recruiting |
| Enrollment | 60 |
| Est. completion date | October 7, 2019 |
| Est. primary completion date | October 7, 2019 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 20 Years to 60 Years |
| Eligibility |
Inclusion Criteria: 1. Male and female patients (age 20-60 years). 2. ASA physical status I and II 3. Patients who are able to breathe spontaneously and lie supine. 4. Patients who have CVP catheter (subclavian or internal jugular vein). Exclusion Criteria: 1. History of carotid artery surgery 2. Significant cardiac disease (cardiomyopathy and/or moderate to severe valvular heart lesion). 3. Significant hepatic disease (Child-Pugh score B or C ). 4. Renal failure. 5. Obesity: BMI ? 30 kg/m2 6. Need for mechanical ventilation. 7. Pregnancy. 8. Unstable vital signs during the process of sonography (e.g. the patients on vasoactive drugs) |
| Country | Name | City | State |
|---|---|---|---|
| Egypt | Beni Suef | Bani Suwayf |
| Lead Sponsor | Collaborator |
|---|---|
| Beni-Suef University |
Egypt,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Common Carotid Artery diameter at expiration (millimetre) | common carotid artery internal diameter changes songraphically measured to assess intravenous resuscitation | 30 minutes before fluid bolus infusion | |
| Primary | Common Carotid Artery diameter at expiration (millimetre) | common carotid artery internal diameter changes songraphically measured to assess intravenous resuscitation | 5 minutesafter fluid bolus infusion | |
| Primary | Central venous pressure (centimetre water) | Central venous pressure changes measured to assess intravenous resuscitation | 5 minutes after fluid bolus infusion |