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A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

Breast Cancer Clinical Trial

Official title:
A Multi-Center, Open Label Phase 1/2 Study of CYT-0851 in Patients With Relapsed/Refractory B-Cell Malignancies and Advanced Solid Tumors

Clinical Trial Summary

This clinical trial is an interventional, active-treatment, open-label, multi-center, Phase 1/2 study. The study objectives are to assess the safety, tolerability and pharmacokinetics (PK) of CYT-0851 in patients with relapsed/refractory B-cell malignancies and advanced solid tumors and to identify a recommended Phase 2 dose as a monotherapy and in combination with chemotherapy for evaluation in these patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Breast Cancer
  • Breast Neoplasms
  • CLL
  • DLBCL
  • Follicular Lymphoma
  • Head and Neck Cancer
  • Lymphoma
  • Lymphoma, Mantle-Cell
  • Malignancy
  • Mantle Cell Lymphoma
  • Multiple Myeloma
  • Neoplasms
  • Non-hodgkin Lymphoma
  • Ovarian Cancer
  • Pancreatic Cancer
  • Sarcoma
  • Small Cell Lung Cancer
  • Small Cell Lung Carcinoma
  • Soft Tissue Sarcoma
  • Squamous Cell Carcinoma of Head and Neck
  • Triple Negative Breast Cancer
  • Triple Negative Breast Neoplasms
Clinical Trial Details
NCT number NCT03997968
Study type Interventional
Source Cyteir Therapeutics, Inc.
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date October 9, 2019
Completion date December 30, 2024
View Details
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