Clinical Trials Logo
  1. Home
  2. Other
  3. NCT03988049

Comparison of 1,550 and 755 Laser in a Split-face Trial

Acne Scars - Mixed Atrophic and Hypertrophic Clinical Trial

Official title:
Comparison of a 1,550 Nanometer Erbium: Glass Fractional Laser and 755-nanometer Alexandrite Picosecond Pulse Duration Laser With Diffractive Lens Array in the Treatment of Acne Scars: a Randomized, Split-face Trial

Clinical Trial Summary

Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison. Patients will receive laser treatments at week 0, week 4, and week 8. Photographs will be taken prior to laser treatment at each visit, and at the week 24 follow-up visit. Photographs will be reviewed by blinded assessors to rate each side of the face and change from baseline photos.

Clinical Trial Description

This is a Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison. Both of these lasers are currently FDA approved for acne scarring. Approximately 18 subjects, men and women with Fitzpatrick skin types I through V and facial acne scarring of grades III-IV (moderate to severe) will be enrolled. Both sides of the participants' face should have similar amount and severity of acne scarring. Participants will be over 18 years old. Patients have to be otherwise healthy without a history of skin cancer, keloidal scarring, localized or active infection, immunodeficiency disorders, and light sensitivity. Patients have to be overall healthy without a history of skin cancer, keloidal scarring, localized or active infection, immunodeficiency disorders, and light sensitivity. Per PI discretion, any serious medical condition that may interfere with the study. In addition, patients who have been taking isotretinoin for a period of 6 months before treatment will be excluded. Patients will have photographs taken at every visit prior to the laser treatments at week 0, week 4, and week 8. Photographs will also be taken at the week 24 follow-up visit. Photos will then be assessed by qualified blinded reviewers for comparison. ;

Study Design

Related Conditions & MeSH terms

  • Acne Scars - Mixed Atrophic and Hypertrophic
  • Hypertrophy
Clinical Trial Details
NCT number NCT03988049
Study type Interventional
Source University of Utah
Contact
Status Completed
Phase N/A
Start date March 8, 2017
Completion date October 30, 2019
View Details
See also
  Status Clinical Trial Phase
Completed NCT04559022 - Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring N/A
Active, not recruiting NCT06192550 - Functional Usability and Feasibility Testing of the Profound Matrix™ System N/A
Recruiting NCT05362929 - Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color N/A
Recruiting NCT05597267 - The MIRIA Acne Scar Study N/A
Completed NCT05691049 - Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face N/A
Active, not recruiting NCT02592993 - Performance of PicoWayTM Picosecond Fractional Laser for Acne Scars N/A
Completed NCT04827680 - Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring N/A
Not yet recruiting NCT05597813 - Topical Timolol 0.5% in Atrophic Acne Scar N/A
Completed NCT03284333 - enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars N/A
Completed NCT03514771 - Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin N/A
Not yet recruiting NCT06102343 - Safety and Efficacy Investigation on the Effects of ClearSkin Non-ablative ER:Glass 1540nm Laser Module in the Treatment of Acne Scars. N/A
Not yet recruiting NCT05600075 - Microneedling With Topical Preparations in the Treatment of Atrophic Post-acne Scars N/A
Not yet recruiting NCT04252352 - Treatment of Acne Scars With Fractional CO2 Laser Versus Radio-frequency Microneedling N/A
Completed NCT04606134 - Tripeptide/Hexapeptide Topical and Hybrid Laser Treatment for Acne Scarring N/A
Completed NCT05358860 - Safety and Efficacy of Sofwave Treatment for Acne Scars Appearance Improvement N/A
Completed NCT04057768 - Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles N/A