Effect of Different Infusion Volume on Perioperative Bladder and Blood Volume in Patients Undergoing Daytime Surgery.

Cholecystolithiasis and Thyroid Nodule Clinical Trial

Official title:

Effect of Different Infusion Volume on Perioperative Bladder and Blood Volume in Patients Undergoing Daytime Surgery.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03924804
• Other study ID #: 20190418
• Status: Completed
• Phase: N/A
• Start date: June 19, 2019
• Est. completion date: May 12, 2022

Study information

• Verified date: May 2022
• Source: China Medical University, China
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The objective of the trial was to explore the effect of different infusion volume on perioperative bladder and blood volume in patients undergoing daytime surgery assisted by bladder and vascular ultrasound and transthoracic echocardiography.

Description:

The objective of the trial was to evaluate the effects of different infusion volume of Ringer's solution acetate (2 ml/kg,8ml/kg, 16ml/kg) on bladder volume, hemodynamics,transthoracic echocardiography and vascular ultrasound including the inferior vena cava(IVC) and the right subclavian vein(SCV) diameter and the IVC and SCV collapsibility index in patients undergoing daytime surgery through a randomized controlled clinical study, so as to provide better guidance for clinical transfusion avoiding bladder catheterization . The patients in this trial were visited before induction and discharge from the postanaesthesia .We also collected the first time and times of micturition and whether the patients have the dysuria.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 90
• Est. completion date: May 12, 2022
• Est. primary completion date: May 12, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 1. ethnic Chinese;
• 2. age, 18 to 65 years old;
• 3. American Society of Anaesthesiologists (ASA) physical status I or II;
• 4. Daytime patients scheduled for general anesthesia

Exclusion Criteria:

• Patients unwilling to cooperate with the experiment
• Body mass index exceeding 30 kg/m2;
• Patients with a history of heart ,liver and Renal failure ,hypertension,diabetes mellitus or arteriosclerosis; and any allergy to drugs used in the study.
• Patients with the urinary diseases, such as kidney, ureteral calculi and tumors, prostatic hypertrophy.

Related Conditions & MeSH terms

• Cholecystolithiasis
• Cholecystolithiasis and Thyroid Nodule
• Cholelithiasis
• Gallstones
• Thyroid Nodule

Intervention

Drug:
• Ringer's solution acetate
Intravenous infusion of 2 ml/kg Ringer's solution acetate within 1 hour after induction.
• Ringer's solution acetate
Intravenous infusion of 8ml/kg Ringer's solution acetate within 1 hour after induction.
• Ringer's solution acetate
Intravenous infusion of 16ml/kg Ringer's solution acetate within 1 hour after induction.

Locations

Country	Name	City	State
China	the First Hospital of China Medical University	Shenyang	Liaoning

Sponsors (1)

Lead Sponsor	Collaborator
China Medical University, China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	1. The change of bladder volume	bladder and blood volume in patients undergoing daytime surgery assisted by bladder and vascular ultrasound	baseline and 10 minutes before leaving the post-anesthesia care unite