Assessment of Intellectual Abilities for Subjects With Velopharyngeal Incompetence and Their Impact on Speech Intelligibility

Velopharyngeal Incompetence Due to Cleft Palate Clinical Trial

Official title:

Assessment of Intellectual Abilities for Subjects With Velopharyngeal Incompetence and Their Impact on Speech Intelligibility

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03898713
• Other study ID #: IQ In VPI patients
• Status: Not yet recruiting
• Start date: July 1, 2019
• Est. completion date: July 1, 2020

Study information

• Verified date: July 2019
• Source: Assiut University
• Contact: Zeinab Soliman, Resident Dr.
• Phone: 01018119004
• Email: smile0smile[@]hotmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To Assess effect of intelligence on speech production on subjects with velopharyngeal incompetence Search if there is any relation between congenital Velopharyngeal incompetence and decrease IQ of patients

Description:

Speech production is a complex process by which thoughts are generated into spoken utterances. Production involves the selection of appropriate words and the appropriate form of those words from the lexicon and morphology, and the organization of those words through the syntax. Then, the phonetic properties of the words are retrieved and the sentence is uttered through the articulations associated with those phonetic properties.

The term intelligibility refers to 'speech clarity' or the proportion of a speaker's output that a listener can readily understand.

Velopharyngeal Incompetence (VPI) refers to any situation in which an individual is unable to completely close the nasal airway during speech. The velopharyngeal mechanism is comprised of a complex group of structures that act in unison to control airflow through the nose and mouth by elevation of the soft palate and constriction of both the lateral and posterior pharyngeal walls. Any disruption in this mechanism may result in abnormal, poorly intelligible speech. VPI can manifest as hypernasality, nasal emission, decreased vocal intensity, and/or facial grimacing.

Intellectual ability refers to the skills required to think critically, see connections between disciplines and problem solve in new or changing situations. Memory, creative problem solving and vocabulary also contribute to the level of an individual's intellectual ability.

Orofacial clefts (OFCs) are frequently occurring human birth defects that have a complex, multifactorial etiology. Though structural orofacial defects are often surgically corrected during infancy and early childhood, OFC patient cohorts are at high risk for neurobehavioral problems including learning disability, impaired language function, psychosocial adjustment issues, and persistently reduced academic achievement.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: July 1, 2020
• Est. primary completion date: July 1, 2020
• Gender: All
• Age group: 3 Years to 25 Years

Eligibility

Inclusion Criteria:

• children with cleft lip and palate primary or secondary repaired

• Velopharyngeal incompetence due to any cause especially short palate and deep pharynx

• children above 3 years

Exclusion Criteria:

• Hearing impairment

• Neurological disease

• ADHD

Related Conditions & MeSH terms

• Cleft Palate
• Velopharyngeal Incompetence Due to Cleft Palate
• Velopharyngeal Insufficiency

Intervention

Diagnostic Test:
• Intelligence quotient
intelligence quotient (IQ) is a total score derived from several standardized tests designed to assess human intelligence

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (3)

Levelt WJ. Models of word production. Trends Cogn Sci. 1999 Jun;3(6):223-232. — View Citation

Robin NH, Baty H, Franklin J, Guyton FC, Mann J, Woolley AL, Waite PD, Grant J. The multidisciplinary evaluation and management of cleft lip and palate. South Med J. 2006 Oct;99(10):1111-20. Review. — View Citation

Waitzman NJ, Romano PS, Scheffler RM. Estimates of the economic costs of birth defects. Inquiry. 1994 Summer;31(2):188-205. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Auditory perceptual assessment	Auditory-perceptual evaluation is the most commonly used clinical voice assessment method, and is often considered a gold standard for documentation of voice disorders.	Baseline
Primary	IQ test	Assess IQ level of patients by standford binet version 4. An intelligence quotient (IQ) is a total score derived from several standardized tests designed to assess human intelligence.; This is to search if there is any relation between IQ level and VPI and effect on speech intelligability	Baseline

External Links

•   Link