The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients

Chronic Periodontitis, Generalized Clinical Trial

Official title:

The Effects of Non -Surgical Periodontal Therapy on Glycemic Control and Periodontal Health in Diabetic Patients With Periodontitis (Randomized Controlled Clinical Trial)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03783845
• Other study ID #: periodontal therapy and HbA1c
• Status: Completed
• Phase: Phase 4
• Start date: June 1, 2015
• Est. completion date: March 30, 2016

Study information

• Verified date: October 2019
• Source: Taibah University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?

Description:

The aim of the present study was to monitor the clinical outcomes and the metabolic response of non-surgical periodontal therapy in patients with chronic periodontitis and uncontrolled type 2 diabetes.

Regarding clinical and metabolic parameters at baseline, no differences were displayed between two groups. However, at 3-months follow-up period the patients within a test group were demonstrated better clinical outcomes than patients in a control group

Recruitment information / eligibility

• Status: Completed
• Enrollment: 44
• Est. completion date: March 30, 2016
• Est. primary completion date: March 1, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 70 Years

Eligibility

Inclusion Criteria:

Diagnosis of diabetes type 2 for more than five years Type 2 diabetes with HbA1c level from 7% to 9% at the last medical evaluation Diagnosis with chronic periodontitis

Exclusion Criteria:

Pregnancy

• Alcoholism and smoking

• Presence of any systemic disorders other than hypertension and diabetes

• Diabetic major complications

Related Conditions & MeSH terms

• Chronic Periodontitis
• Chronic Periodontitis, Generalized
• Periodontitis

Intervention

Combination Product:
• amoxicillin 500mg and metronidazole 400mg
metronidazole 400mg and amoxicillin 500mg three times daily for two weeks

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Taibah University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	glycosylated haemoglobin (HbA1c)	Blood was taken from a peripheral vein to monitor HbA1c using high-performance liquid chromatography	3 months