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Clinical Trial Summary

The aim of this prospective randomized clinical trial was compare between 2% Mepivacaine and 4% Articaine for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis in mandibular molars as regards to their anesthetic efficiency; during access cavity preparation and instrumentation.


Clinical Trial Description

Sixty-six patients diagnosed clinically and radiographically with symptomatic irreversible pulpitis in mandibular posterior teeth will received single-visit root canal treatment using ProTaper Universal rotary system for canal preparation, then they will be randomly divided into two groups (n=33) according to the anesthetic solution used, either Group M (3.6 ml Mepivacaine hydrochloride 2% with 1:100000 epinephrine) or Group A (3.4 ml Articaine hydrochloride 4% with 1:100000 epinephrine). The pain will be assessed using numerical rating scale (NRS) during access cavity preparation and instrumentation, then the need for supplemental anesthesia will be also recorded. ;


Study Design


Related Conditions & MeSH terms

  • Pulpitis
  • Symptomatic Irreversible Pulpitis

NCT number NCT03725579
Study type Interventional
Source Cairo University
Contact Marwa M Bedier, PHD
Phone 0021006611104
Email m.bedier81@gmail.com
Status Recruiting
Phase Phase 2/Phase 3
Start date September 15, 2018
Completion date December 2018

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