Other Clinical Trial - Chewed Versus Integral Pill of Ticagrelor

Status Completed

Clinical Trial Summary

Hypothesis The primary question the investigators propose to answer is whether all patients undergoing percutaneous coronary intervention (PCI) with stent deployment who receive chewed ticagrelor will demonstrate more rapid drug absorption and decreased platelet reactivity as compared to integral pill form 1 hour after drug administration.

Clinical Trial Description

Hypothesis The primary question the investigators propose to answer is whether all patients undergoing PCI with stent deployment who receive chewed ticagrelor will demonstrate more rapid drug absorption and decreased platelet reactivity as compared to integral pill form 1 hour after drug administration. Secondary Hypotheses: 1. Major adverse cardiac and cerebrovascular event (MACCE) rate at 30 days and 1 year. 1. Death 2. Repeat myocardial infarction 3. Need for urgent revascularization 4. Cerebrovascular accident 2. Rate of stent thrombosis and in-stent stenosis at 30 days and 1 year. 3. Bleeding: Defined as major, minor, or minimal bleeding based on thrombolysis in myocardial infarction (TIMI) criteria. ;

Study Design

Related Conditions & MeSH terms

Percutaneous Coronary Intervention

Clinical Trial Details

NCT number	NCT03708588
Study type	Interventional
Source	Aurora Health Care
Contact
Status	Completed
Phase	Phase 4
Start date	September 19, 2018
Completion date	July 31, 2021

View Details

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