Mycological Comparative Study on Maxillary Dentures of Two Different Materials

Effect of Tio2 Nanoparticles on Candida Aggregation Clinical Trial

Official title:

Mycological Comparative Study Between Single Maxillary Denture Fabricated From Rapid Heat Cure Acrylic Resin Material and Conventional Acrylic Resin Material Modified by Titanium Dioxide Nanoparticles

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03700489
• Other study ID #: Acrylic vs Tio2 reinforced
• Status: Not yet recruiting
• Phase: N/A
• Start date: October 20, 2018
• Est. completion date: June 1, 2019

Study information

• Verified date: October 2018
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Cross over design the investigator divide participants to two groups group (A) will receive rapid heat cured denture base material and group (b) will receive the acrylic denture modified by titanium dioxide nanoparticles and after washout period alternatively group (a) will receive the acrylic denture modified by titanium dioxide nanoparticles AND group (b) will receive rapid heat cured denture base material the investigator will take swaps from dentures to count the candida species

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 34
• Est. completion date: June 1, 2019
• Est. primary completion date: May 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 30 Years to 55 Years

Eligibility

Inclusion Criteria:

• Completely edentulous maxillary arch and partially dentate mandibular arch with adequate interarch space.

• The edentulous ridges should be covered by firm healthy mucosa.

• Angle class I maxillomandibular relation.

• Healthy and cooperative patient

Exclusion Criteria:

• Patients with bad habits as severe clenching or bruxism, drug or alcohol addiction, moderate or heavy smoking (greater than 10 cigarettes per day).

• Previous history of radiotherapy or chemotherapy.

• Any skeletal problem dictates surgical intervention

Related Conditions & MeSH terms

• Effect of Tio2 Nanoparticles on Candida Aggregation

Intervention

Other:
• titanium dioxide denture
patients will receive titanium dioxide denture (made from acrylic resin with titanium dioxide nanoparticles ) for 1 month in the initial phase then in the second phase after one month they will receive( rapid heat cured acrylic resin)denture according to the principle of crossover des

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ali ibrahim mahmoud shamardal

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mycological investigation	Count of candida on the fitting surface of denture by (CFU) unit	6 months