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Clinical Trial Summary

Coagulation disorders are on top of the list of extracorporeal-membrane oxygenation (ECMO) complications. They contribute significantly to morbidity and mortality of ECMO patients. This observational study aims to evaluate coagulation profiles of ECMO patients treated on the intensive care units of the Department of Anaesthesiology of LMU Munich.


Clinical Trial Description

Coagulation disorders are on top of the list of extracorporeal-membrane oxygenation (ECMO) complications. They contribute significantly to morbidity and mortality of ECMO patients. This observational study aims to evaluate coagulation profiles of ECMO patients treated on the intensive care units of the Department of Anaesthesiology of LMU Munich. Adult ECMO patients are included in the study after informed consent. Bleeding and thromboembolic complications as well as treatment details are recorded. Additional coagulation laboratory markers (such as von-Willebrand-factor, ADAMTS13-protease, platelet function tests and thromboelastometric tests) are correlated with clinical signs of bleeding. Regular ultrasound examination of the large vessels are performed to Screen for thrombosis. ;


Study Design


Related Conditions & MeSH terms

  • Coagulation and Hemorrhagic Disorders
  • Extracorporeal Membrane Oxygenation Complication
  • Hemorrhagic Disorders

NCT number NCT03642912
Study type Observational
Source Ludwig-Maximilians - University of Munich
Contact
Status Active, not recruiting
Phase
Start date January 16, 2019
Completion date December 31, 2022

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