Frontotemporal Lobar Degeneration Clinical Trial
— DLFTOfficial title:
Multidisciplinary and Personalized Care of Behavioral Disorders in Frontotemporal Lobar Degeneration.
Verified date | March 2022 |
Source | University Hospital, Bordeaux |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Fronto-Temporal Lobar Degeneration (FTLD) refers to 3 categories of neurodegenerative diseases generally occurring between 55 and 65 years: Fronto-Temporal Dementia(FTD), Primary Progressive Aphasia (PPA), Semantic Dementia (SD). Clinical expression is substantially variable among individuals, but in most cases, behavioural disorders and personality changes are prominent. FTLD is poorly known by general public including health care professionals. Currently, the French health system does not meet the needs and expectations of patients and their families
Status | Completed |
Enrollment | 38 |
Est. completion date | October 6, 2021 |
Est. primary completion date | October 6, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion criteria: Patients - Fronto-Temporal Lobar Degeneration diagnoses - Men or women aged 18 and over Caregiver • Spouse, brother, sister, child living at patient's home and can provide the medical team of reliable information on the status of their parent. Exclusion criteria : Patient - Patient institutionalized - Pregnant or breast-feeding woman - Psychotic syndrome - Severe and unstable general medical condition - Patient bedridden Caregiver - Persons under legal protection - Severe and unstable general medical condition - Pregnant or breast-feeding woman |
Country | Name | City | State |
---|---|---|---|
France | Bordeaux University Hospital | Bordeaux |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Bordeaux |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Neuropsychiatric Inventory (NPI) | Assessment of neuropsychiatric symptomatology | 6 months | |
Secondary | Neuropsychiatric Inventory (NPI) | Assessment of neuropsychiatric symptomatology | 12 months | |
Secondary | Mini Mental State Examination | 6 months and 12 months | ||
Secondary | Frontal Behavioral Inventory | 6 months and 12 months | ||
Secondary | Frontal Assessment Battery | 6 months and 12 months | ||
Secondary | Geriatric Depression Scale Score ( From 0 to 30) | Score : 0 - 5 : normal Score : 5 - 9 : light depression Score : 10 - 30 : severe depression | 6 months and 12 months | |
Secondary | Sense of Competence Questionnaire (SCQ) | 6 months and 12 months | ||
Secondary | Quality of Life Questionnaire (QoL-AD) | 6 months and 12 months | ||
Secondary | Hierarchical scale of internality for elderly people (EHIPA) score ( From 0 to 22) | The score varies from 0 to 22. A high score corresponding to an important internality | 6 months and 12 months |
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