Clinical Feature and Treatment of Microsporidial Keratoconjunctivitis

Microsporidial Keratoconjunctivitis Clinical Trial

— MKC  

Official title:

Clinical Feature and Treatment of Microsporidial Keratoconjunctivitis

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03555409
• Other study ID #: 201805063RINA
• Status: Recruiting
• Start date: June 1, 2018
• Est. completion date: May 31, 2019

Study information

• Verified date: May 2018
• Source: National Taiwan University Hospital
• Contact: I-Jong Wang
• Phone: 886-2-23123456
• Email: ijong[@]ntu.edu.tw
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this project was to analysis the causes, pathogenesis, diagnostic modalities and treatment outcomes of microsporidial keratoconjunctivitis.

Description:

Microsporidia comprise a diverse group of obligate spore-forming intracellular eukaryotic pathogens first described in immunocompromised patients. Many species of microsporidia are found in aquatic environments, and they are considered as waterborne pathogens.Microsporidia are opportunistic pathogens that are reported to cause infections in various organs, including the eyes. The ocular appearance of this infection can manifest as corneal stromal keratitis or a superficial punctate keratoconjunctivitis. In particular, the characteristic feature of microsporidial keratoconjunctivitis is multiple whitish, slightly elevated epithelial lesions in conjunction with acute conjunctivitis. Awareness of microsporidial keratoconjunctivitis is increasing, and the number of cases reported is on the rise. This study was a retrospective case series of patients diagnosed as microsporidial keratoconjunctivitis. The purpose of this project was to analysis the causes, pathogenesis, diagnostic modalities and treatment outcomes of microsporidial keratoconjunctivitis

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 20
• Est. completion date: May 31, 2019
• Est. primary completion date: May 31, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 7 Years and older

Eligibility

Inclusion Criteria:

• Patients diagnosed as microsporidial keratoconjunctivitis

Exclusion Criteria:

• Patients diagnosed as bacterial or viral keratoconjunctivitis

Related Conditions & MeSH terms

• Keratoconjunctivitis
• Microsporidial Keratoconjunctivitis

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Full chart records of the patients who diagnosed as microsporidial keratoconjunctivitis	Charts of all patients diagnosed as microsporidial keratoconjunctivitis between January, 2008 and April, 2018 at National Taiwan University Hospital were reviewed.	2018/6/1-2019/5/31