Randomized Pilot Trial of Antimicrobial Therapy and Stereotactic Body Radiation Therapy in Early-stage Non-small Cell Lung Cancer

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Early Stage Non-Small Cell Lung Cancer Clinical Trial

Official title:
Randomized Pilot Trial of Antimicrobial Therapy and Stereotactic Body Radiation Therapy in Early-stage Non-small Cell Lung Cancer

Status Recruiting

Clinical Trial Summary

To determine if the addition of vancomycin to SBRT increases a Th1 immune response measured by cytokine expression (IFN gamma)

n/a

NCT number	NCT03546829
Study type	Interventional
Source	Abramson Cancer Center at Penn Medicine
Contact	Ching Lai
Phone	267-250-9244
Email	ching.lai@pennmedicine.upenn.edu
Status	Recruiting
Phase	Early Phase 1
Start date	April 24, 2018
Completion date	December 31, 2027

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04530227` - Camrelizumab With Chemotherapy in Adults With Medically Inoperable Early Stage NSCLC	Phase 2
Terminated	`NCT03050554` - Stereotactic Body Radiation Therapy (SBRT) Combined With Avelumab (Anti-PD-L1) for Management of Early Stage Non-Small Cell Lung Cancer (NSCLC)	Phase 1/Phase 2
Terminated	`NCT01138722` - Predicting Cell Death by Radiation Therapy in Early Stage Non-small Cell Lung Cancer: a Prospective Translational Trial	Phase 2
Completed	`NCT03916367` - CT-guided Radioactive I-125 Seeds Implantation for Early Stage Lung Cancer
Recruiting	`NCT05785845` - Computed Tomography-Guided Stereotactic Adaptive Radiotherapy (CT-STAR) for the Treatment of Central and Ultra-Central Early-Stage Non-Small Cell Lung Cancer	N/A