Effects of Kale Ingredients on Lipid Status Parameter Clinical Trial
— HypocholKaleOfficial title:
Investigations on the Effect of Kale on the Lipid Status (Untersuchungen Zum Einfluss Von Grünkohl Auf Den Lipidstatus)
This intervention study investigates the effects of various kale preparations (dietary supplements) on lipid status parameters. Within the study period of 8 weeks, three blood withdrawals are planned (week 0, 4 and 8) for the volunteers. Lipid status parameters (total cholesterol, HDL cholesterol, LDL cholesterol, triacylglycerides) will be determined in blood. There is a correlation between contents of LDL cholesterol, total cholesterol and triacylglycerides and the risk for cardiovascular diseases (CVD). In contrast, a high content of HDL cholesterol is correlated with a lower risk for CVD. In addition, the contents of apolipoprotein A1 and apolipoprotein B will be analysed.
Status | Recruiting |
Enrollment | 40 |
Est. completion date | December 2020 |
Est. primary completion date | September 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - total cholesterol > 200 mg/dl Exclusion Criteria: - LDL cholesterol < 130 mg/dl - medication to lower blood lipids - genetically based hypercholesterolemia |
Country | Name | City | State |
---|---|---|---|
Germany | Friedrich Schiller University, Institute iof Nutritional Science | Jena | Thuringia |
Lead Sponsor | Collaborator |
---|---|
University of Jena |
Germany,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change of lipid status parameters | total cholesterol, HDL cholesterol, LDL cholesterol | weeks 0, 4 and 8 | |
Secondary | Change of apolipoproteins | apolipoprotein A1 and apolipoprotein B | weeks 0, 4 and 8 | |
Secondary | Change of antioxidant capacity | lipophilic antioxidant capacity (L-TEAC) | weeks 0, 4 and 8 |