WGS of NTM From Sputum of NTM Lung Disease Patients and From Their Environments — NTM_HOME  

Nontuberculous Mycobacterium Infection Clinical Trial

Official title: Whole Genome Sequencing of Nontuberculous Mycobacterium (NTM) Derived From Sputum Specimen of NTM Lung Disease Patients Living Together and From Their Environmental Samples

Status Recruiting

Clinical Trial Summary

The purpose of the study is to identify the genetic closeness of NTM derived from patients living together and from their surrounding environment and to trace the temporal relationship between them.

Clinical Trial Description

After NTM isolation is done by using culture, from patients' sputum/bronchoscopic samples and their environmental samples, whole genome sequencing (WGS) will be conducted for all NTM isolates. Phylogenetic analysis will be performed based on single nucleotide polymorphism (SNP) on each NTM. ;

Related Conditions & MeSH terms

• Lung Diseases
• Mycobacterium Infections
• Mycobacterium Infections, Nontuberculous
• Nontuberculous Mycobacterium Infection
• Whole Genome Sequencing

• NCT number: NCT03532438
• Study type: Observational [Patient Registry]
• Source: Seoul National University Hospital
• Contact: Jae-June Yim, MD
• Phone: +82-2-2072-2059
• Email: yimjj@snu.ac.kr
• Status: Recruiting
• Start date: May 2018
• Completion date: May 2019