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Clinical Trial Details — Status: Suspended

Administrative data

NCT number NCT03526172
Other study ID # UMT057/13
Secondary ID
Status Suspended
Phase
First received
Last updated
Start date February 26, 2019
Est. completion date December 2022

Study information

Verified date November 2021
Source University of Winchester
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

High tibial osteotomy (HTO is often indicated in physically active patients. The insertion of a bone graft during surgery has been shown to have good clinical and biomechanical outcomes, however objective data regarding post-surgery physical activity (PA) levels in patients who have undergone HTO with and without bone grafts does not exist in the literature. Using accelerometers and questionnaires, this study will be the first to investigate this in an objective way.


Recruitment information / eligibility

Status Suspended
Enrollment 60
Est. completion date December 2022
Est. primary completion date December 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Patient undergoing unilateral medial opening wedge high tibial osteotomy at Basingstoke & North Hampshire Hospital, UK Exclusion Criteria: - Concurrent procedures during HTO surgery - The use of an off-loader knee brace in the 3 weeks leading up to surgery - Revision surgery

Study Design


Related Conditions & MeSH terms

  • High Tibial Osteotomy With Allograft Wedge
  • High Tibial Osteotomy Without Allograft Wedge
  • Pre- and Post-operative Physical Activity Levels

Intervention

Procedure:
High tibial osteotomy
Uni-lateral medial opening-wedge high tibial osteotomy following a minimally invasive approach.
Device:
Allograft wedge
Insertion of allograft wedge into the osteotomy gap during the HTO procedure
Accelerometer
ActivPal accelerometer attached to thigh of patient to collect objective physical activity data at pre-determined intervals before and after surgery
Other:
Questionnaire
Validated clinical questionnaires administered to patients to collect subjective physical activity data at pre-determined intervals before and after surgery

Locations

Country Name City State
United Kingdom University of Winchester Winchester

Sponsors (2)

Lead Sponsor Collaborator
University of Winchester Hampshire Hospitals NHS Foundation Trust

Country where clinical trial is conducted

United Kingdom, 

References & Publications (4)

Copeland JL, Esliger DW. Accelerometer assessment of physical activity in active, healthy older adults. J Aging Phys Act. 2009 Jan;17(1):17-30. — View Citation

Eisenberg MH, Phillips LA, Fowler L, Moore PJ. The Impact of E-diaries and Accelerometers on Young Adults' Perceived and Objectively Assessed Physical Activity. Psychol Sport Exerc. 2017 May;30:55-63. doi: 10.1016/j.psychsport.2017.01.008. Epub 2017 Jan 31. — View Citation

Falck RS, Landry GJ, Brazendale K, Liu-Ambrose T. Measuring Physical Activity in Older Adults Using MotionWatch 8 Actigraphy: How Many Days are Needed? J Aging Phys Act. 2017 Jan;25(1):51-57. doi: 10.1123/japa.2015-0256. Epub 2016 Aug 24. — View Citation

Martins RC, Reichert FF, Bielemann RM, Hallal PC. One-year Stability of Objectively Measured Physical Activity in Young Brazilian Adults. J Phys Act Health. 2017 Mar;14(3):208-212. doi: 10.1123/jpah.2015-0384. Epub 2016 Dec 20. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Objective physical activity levels (measured in steps per day) Physical activity data (step-count and body position) collected via an accelermeter that is attached to the thigh for 7 day periods at pre-determined intervals before and after surgery 14 weeks per patient
Primary Intensity of physical activity (measured in steps per minute) Physical activity data (step-count and body position) collected via an accelermeter that is attached to the thigh for 7 day periods at pre-determined intervals before and after surgery 14 weeks per patient
Secondary Subjective reasons, thoughts and feelings behind post-operative physical activity levels (thematic analysis) interviews with fully healed patients to determine their reasons, thoughts and feelings behind their post-operative levels of physical activity 1 hour per patient
Secondary Subjective physical activity levels Physical activity data (step-count and body position) collected via the implementation of validated questionnaires at pre-determined intervals before and after surgery 14 weeks per patient